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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTK
All Species:
11.52
Human Site:
Y242
Identified Species:
21.11
UniProt:
P33981
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33981
NP_003309.2
857
97072
Y242
T
T
K
A
R
F
L
Y
G
E
N
M
P
P
Q
Chimpanzee
Pan troglodytes
XP_001146752
857
97034
Y242
T
T
K
A
R
F
L
Y
G
E
N
L
P
P
Q
Rhesus Macaque
Macaca mulatta
XP_001111082
778
87619
L203
S
E
E
E
K
K
T
L
S
A
S
M
V
L
T
Dog
Lupus familis
XP_539016
855
96614
F240
G
Q
T
T
K
A
R
F
L
Y
G
E
N
L
P
Cat
Felis silvestris
Mouse
Mus musculus
P35761
856
96192
Y238
A
G
A
A
R
V
L
Y
G
E
N
L
P
P
Q
Rat
Rattus norvegicus
NP_001101642
835
94323
S220
S
S
L
G
N
L
Q
S
R
K
S
S
C
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512474
935
104827
E245
G
A
R
F
L
N
G
E
N
I
S
P
Q
D
I
Chicken
Gallus gallus
XP_419867
879
99691
L246
F
V
R
L
S
V
L
L
E
E
K
S
Q
D
H
Frog
Xenopus laevis
NP_001082090
882
99060
S244
Y
S
V
K
T
R
F
S
Y
G
E
K
L
S
S
Zebra Danio
Brachydanio rerio
Q8AYG3
982
109993
S304
T
P
D
G
D
S
Y
S
L
N
I
K
P
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002301009
818
91361
D217
N
F
Q
N
M
E
S
D
V
T
S
R
S
D
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565160
777
86358
S202
P
S
V
D
S
E
V
S
L
K
S
E
Y
K
D
Baker's Yeast
Sacchar. cerevisiae
P54199
764
86809
P189
V
P
N
S
P
N
Q
P
I
N
A
R
E
T
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
85.7
87.4
N.A.
74.3
76.9
N.A.
64.2
61
52.8
41.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
87.7
92.6
N.A.
84.8
85.6
N.A.
73.6
74.5
68.4
57
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
6.6
0
N.A.
66.6
0
N.A.
0
13.3
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
33.3
13.3
N.A.
73.3
26.6
N.A.
13.3
20
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
23.1
N.A.
N.A.
22.9
22.7
N.A.
Protein Similarity:
40.2
N.A.
N.A.
42.3
44.5
N.A.
P-Site Identity:
0
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
26.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
24
0
8
0
0
0
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
8
8
8
0
0
8
0
0
0
0
0
31
8
% D
% Glu:
0
8
8
8
0
16
0
8
8
31
8
16
8
0
0
% E
% Phe:
8
8
0
8
0
16
8
8
0
0
0
0
0
0
0
% F
% Gly:
16
8
0
16
0
0
8
0
24
8
8
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
8
8
8
0
0
0
8
% I
% Lys:
0
0
16
8
16
8
0
0
0
16
8
16
0
8
0
% K
% Leu:
0
0
8
8
8
8
31
16
24
0
0
16
8
16
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
16
0
0
0
% M
% Asn:
8
0
8
8
8
16
0
0
8
16
24
0
8
0
0
% N
% Pro:
8
16
0
0
8
0
0
8
0
0
0
8
31
31
16
% P
% Gln:
0
8
8
0
0
0
16
0
0
0
0
0
16
0
24
% Q
% Arg:
0
0
16
0
24
8
8
0
8
0
0
16
0
0
0
% R
% Ser:
16
24
0
8
16
8
8
31
8
0
39
16
8
8
8
% S
% Thr:
24
16
8
8
8
0
8
0
0
8
0
0
0
8
8
% T
% Val:
8
8
16
0
0
16
8
0
8
0
0
0
8
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
8
24
8
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _